Custom Peptides
Cayman Chemical ClInofIbrate 10mg
A hypolipidemic agent; inhibits HMG-CoA reductase (IC50 = 0.47 mM); stimulates the S-indan-1-ol dehydrogenase activity of human liver AKR 1C4; reduces serum cholesterol and triglyceride levels in rats fed a normal chow pellet diet or a semisynthetic diet containing sucrose as the only carbohydrate source at 10 and 30 mg/kg
Cayman Chemical 5-fluoro 203 10mg
A cytotoxic compound that at 1 µM activates aryl hydrocarbon receptor signaling, inducing transcription of cytochrome P450 1A1, which leads to the formation of DNA adducts and cell cycle arrest; can increase the levels of ROS as well as activate JNK, ERK, and p38MAPK in certain ovarian, breast, kidney, and colorectal cancer cells
Genelink Random Hexamers, 100 μg, 6 bases, 5'-d(NNNNNN)-3', Equimolar 25% A, C, G, T, ~54 nmol/molecule, HPLC purified
Random Hexamers (100 μg) from GENELINK are a versatile mixture of oligonucleotides, six bases in length, designed for a range of molecular biology applications. These primers are crucial for processes like DNA probe labeling, first-strand cDNA synthesis, and the detection of genetic variations. The random nature of the sequence allows for extensive coverage of target DNA or RNA templates, making them ideal for numerous genomic studies.
- Facilitates DNA probe labeling, cDNA synthesis, and RAPD analysis.
- Enables production of high specific activity labeled DNA probes for sensitive detection.
- Provides random initiation sites across varied RNA templates.
- Supports identification of genetic variations for genetic mapping.
Cayman Chemical OrItavncInphosphate 10mg
A semisynthetic glycopeptide antibiotic that inhibits the growth of Gram-positive bacteria; inhibits the growth of clinical isolates of MRSA, MSSA, VREF, VSRF, and other staphylococci, streptococci, and enterococci (MIC90s = ≤0.008-0.5 mg/L); inhibits growth of S. aureus in a neutropenic-mouse thigh model of infection (ED50 = 0.95 mg/kg for single dose); improves survival of mice in an inhalation model of B. anthracis Ames anthrax
Cayman Chemical ISOLIQUIRITIN 10MG
A flavonoid with diverse biological activities; inhibits LPS-induced nitrite and PGE2 production in RAW 264.7 cells at 1.6 µM; inhibits tube formation by isolated rat aortic endothelial cells from 5-500 UG/ml; reduces carmine content and pouch fluid weight in a mouse model of adjuvant-induced pouch granuloma formation (ED50s = 1.46 and 0.771 mg/kg, respectively); increases cortical, hippocampal, and hypothalamic 5-HT and norepinephrine levels and decreases immobility time in the forced swim and tail suspension tests in mice from 10-40 mg/kg
Cayman Chemical FluocInonIde 10mg
A synthetic corticosteroid that binds to the glucocorticoid receptor; prevents inflammation and epidermal cell proliferation; inhibits tumor promotion and DNA synthesis in mouse epidermis when applied topically at a dose of 10 UG/0.2 ml; an agonist at the Smo receptor (EC50 = 1,000 nM)
Cayman Chemical MeOSucRPYpNAtrIfluoroace 10mg
A colorimetric serine protease substrate; cleavage of the RPY peptide sequence releases pNA, which can be quantified by colorimetric detection at 405 nm as a measure of serine protease activity
Cayman Chemical Bavachalcon 10mg
A chalcone and flavonoid with diverse biological activities; inhibits α-glucosidase, UGT1A1, and UGT1A7 (IC50s = 11.1, 11.3, and 3.6 µM, respectively); cytotoxic to K562 cells (IC50 = 2.77 µM); inhibits RANKL-induced osteoclastogenesis of isolated mouse BMDMs at 5 UG/ml
Cayman Chemical 1 2DIpalmItoloyl3PalmItoy 10mg
A triacylglycerol; has been found in male B. lapidaries bumblebee fat bodies
Cayman Chemical BalaglItazon 10mg
A partial agonist of PPARγ (EC50 = 1.351 μM in a transactivation assay); decreases non-fasting plasma glucose levels in diabetic db/db mice (ED90 = 3 mg/kg per day); decreases plasma levels of insulin and glucose in an oral glucose tolerance test in diet-induced obese rats at 5 and 10 mg/kg per day; in doxorubicin-resistant K562 human myelogenous leukemia cells, it decreases P-gp levels, increases intracellular accumulation of rhodamine 123, and sensitizes cells to doxorubicin at 25 μM
Cayman Chemical CephalosporIn CzInc 10mg
A cephalosporin antibiotic; active against a variety of bacteria, including S. pyogenes, C. diphtheriae, E. coli, and H. influenzae (MICs = 31, 15.6, 125, and 31 UG/ml, respectively), as well as clinical isolates of N. gonorrhoeae (MICs = 1.9-15.6 UG/ml)
Cayman Chemical 7-APDBhydrochlorIde 10mg
An analytical reference standard categorized as a benzofuran; intended for research and forensic applications
Cayman Chemical GnoderenIc AcId D 10mg
A triterpenoid with diverse biological activities; inhibits ACE (IC50 = 734 µM); cytotoxic to HepG2, HeLa, and Caco-2 cancer cells (IC50s = 0.14, 0.18, and 0.26 mg/ml, respectively); inhibits LPS-induced NO production in BV-2 microglia (IC50 = 13.77 µM)
Cayman Chemical L-MoseshydrochlorIde 10mg
A PCAF bromodomain inhibitor (Kd = 126 nM); selective for PCAF over GCN5 (Kd = 600 nM); >4,500-fold selective for PCAF over BRD4; displaces the PCAF bromodomain from histone H3.3 in a nanoBRET target engagement assay at 5 μM